Sample Testing

A comprehensive biomarker strategy covers a range of specialty assays that are fit-for-purpose, and can be custom-designed and fully validated, if needed.   We can deliver these assays as individual pieces or as a package of assays that are analyzed together via our propriety analytics platform, delivering unprecedented insights to sponsors.   Our pre-eminent scientific team includes individuals with decades of academic and industry experience, hundreds of publications, and direct experience in creating some of the industry’s pioneering marketed immunotherapy products.

Immune Monitoring

• Assessment of immune cell function and enumeration

• Array of platforms from flow cytometry to ELISpot

• Mix of standard and customizable panels of flow-cytometry panels

• Cell-surface and intracellular markers, phosphorylated markers

• Custom assay development and validation of novel markers and antigen-specific T- and B-cell assays

Cell-based and ligand-binding assays

• Cytokine production / secretion

• Custom assays to measure specific markers of interest

• PK and ADA (anti-drug antibody) assessments for protein products

Imaging

• Various imaging techniques for solid tumor studies such as Immunohistochemistry (IHC) and Fluorescent in-situ Hybridization (FISH)

Molecular assays

• Next Generation Sequencing (NGS)

• Genotyping

• DNA / RNA Expression analysis

• BCR / TCR Sequencing through partner labs

PBMC isolation

• Global isolation and storage of specimens for future testing

• Over 1 million samples processed globally each year

 

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